I can hear my guitar using Direct Monitor on the Solo and I can record it into Audacity without issue. If I go into ProTools, I can change from Input 1 to Input 2 and then be able to hear my guitar in real-time. For GFX, I can hear it in the right channel for about 2 seconds upon program startup, but then just a little bit of hiss (which changes character when I mess around with preset settings). No difference between using Windows Audio and ASIO. Active Audio Input channels 1+2 are set. If I plug a mic into the XLR input of the Scarlett, I can hear my own voice then. So basically it seems the software is ignoring the instrument input. Could I get any help with this?